Impact of Iron Oxide Containing Formulations Against Visible Light Induced Skin Pigmentation in Skin of Color Individuals


Visible light (400–700nm), which contributes to 45% of solar radiation, contributes to skin darkening and worsening dyschromia, particularly in individuals with Fitzpatrick skin phototypes III and higher. Currently, sunscreens provide limited protection against that spectrum. Due to their capabilities in absorbing, scattering, and reflecting visible light, topical products containing pigments and metal oxides can provide additional photoprotection. This study evaluated the efficacy of two formulations containing iron oxide in preventing visible light-induced pigmentation compared with a non-tinted mineral SPF 50+ sunscreen. Expert grading and colorimetry demonstrated that the iron-oxide-containing formulations significantly protected against visible light-induced pigmentation compared to untreated skin or mineral SPF 50+ sunscreen in Fitzpatrick IV individuals. These results highlight that iron-oxide-containing formulas in a foundation format have dual functions and can provide additional benefits in patients' daily routines by masking existing pigmentation and preventing the development of pigmentation triggered by sunlight exposure, extending protection beyond the UV spectrum. At the earth’s surface, solar radiation comprises 5†"7% ultraviolet (UV), 45% visible light (VIS), and 48†"50% infrared (IR) radiation.1 Studies on the cutaneous impact of radiation have focused on UVB and UVA-mediated effects on the skin. UVA and UVB are shown to contribute to erythema, tanning, photoaging, and skin cancers through different mechanisms.2 If you are looking for high quality, high purity, and cost-effective Iron Oxide, or if you require the latest price, please email contact mis-asia.

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