New calcium phosphate bone cement can achieve self-healing function
The advent of new calcium phosphate cement
According to foreign media reports, a substance called calcium phosphate bone cement has been widely used in human fracture repair surgery, this substance can not only fix the bone together, but also promote the growth of new bone tissue. Now, scientists have added carbon fiber material to this material, so that it can have excellent self-healing function. In the current situation, calcium phosphate bone cement is usually injected into the fracture site as a paste.
The polymerized ethylamine urea is mixed with the contact agent to form a liquid polymer, which acts chemically into a foam state, is stable in 15-20 minutes, and completely hardens after 24-48 hours. If it is poured into the bone cavity, the bone can be joined, and after hardening, it can be allowed to do functional activities and proper weight-bearing. There is no allergic or poisoning reaction locally and throughout the body, and it is gradually replaced because it has a foam structure. Use dog test results for new bones after 18-24 months. Therefore, it is also called absorbable intramedullary needle. According to reports, this substance can be used for fresh fractures, delayed or non-connected fractures, osteotomy, joint fixation, pathological fractures, and filling of bone defects. When joining, the bone must be dug out of the groove and the medullary cavity hollowed out, and then Ostamet is poured.
Disadvantages of the old calcium phosphate cement
Although the strength of calcium phosphate bone cement will become hard, it will also become very brittle at the same time, which means that it may also break when subjected to heavy loads. These cracks will then widen and eventually cause the implant material to break. This is like a crack in a concrete building that will eventually cause them to collapse. Because of this shortcoming, cement is usually only used in bones that do not support weight.
Study on a new type calcium phosphate bone cement
Researchers from Friedrich Schiller University in Jena, Germany collaborated with researchers from the University of Würzburg. They solved this problem by adding carbon fiber to the common calcium phosphate bone cement, so that it can be done in two ways. solve this problem.
Frank A. Müller, a professor at the University of Jena, explained: "First of all, these fibers significantly improve the damage resistance of cement because they act as a bridge when cracks are formed to prevent further expansion of the cracks. Second, we conducted a fiber surface Chemical activation experiment. This means that once the exposed fibers come into contact with body fluids, these body fluids will accumulate in the opening formed by the crack, and the mineralization process will begin. The resulting apatite-the basic composition of bone tissue Part-will bridge the crack again."
As of now, the test includes intentionally cracking the carbon fiber reinforced cement and putting it in simulated body fluids for healing. Once further development is possible, this technology will hopefully allow calcium phosphate bone cements to be applied to a wider range of bones, including those affected by mechanical loads.