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Iron Oxide Nanoparticles

Iron oxides are compounds that are composed of iron and oxygen. Various types of iron oxides include iron(II) oxide, wüstite (FeO), magnetite (Fe3O4), iron(III) oxide (Fe2O3), alpha phase, hematite (α-Fe2O3), beta phase, (β-Fe2O3), gamma phase, maghemite (γ-Fe2O3), epsilon phase, (ε-Fe2O3). Magnetite, maghemite, and hematite are the most common forms existing naturally (M. et al., 2011). Iron oxide NPs have promising characteristics to be used for theranostics in cancer. The attachment of iron oxide NPs to the surface of anticancer drugs facilitates precise tumor imaging in one step by magnetic resonance and as a targeted therapy.

An example is a study carried out for the preclinical investigation of the biocompatibility of a new iron oxide-based nanoparticle coated with L-DOPA to improve its dispersion in biological media. Results revealed that NPs have perhaps caused the induction of local inflammation and subsequent employment of the peripheral lymphocytes. However, the reduction in the platelet counts may reflect tissue lesions triggered by NPs (Comănescu et al., 2015). In another study, superparamagnetic iron oxide NPs (SPIONs) have been synthesized and investigated as agents for directly labeling cells for stem cell imaging. High-quality, monodisperse, and biocompatible DMSA-coated SPIONs have been attained by a thermal decomposition followed by a ligand exchange reaction. However, the attained results have revealed a limited influence of SPIONs on treated skeletal myoblasts without interfering with the basic cell functions (Wierzbinski et al., 2018). If you are looking for high quality, high purity and cost-effective Iron oxide, or if you require the latest price of Iron oxide, please feel free to email contact mis-asia.

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